Ocustat

Eye Doctor Recommended

OcuSTAT™

Dietary Supplement for Computer Users
Supports Ocular Health during Electronic Device Exposure†

What Is OcuStat?

OcuStat™ is a comprehensive multivitamin and multimineral formula, with key phytonutrients and carotenoids, specifically designed to support the ocular health of computer users. These nutrients help to contribute to a healthy macula, retina and visual performance for all ages affected by excess blue-light exposure and free radical damage that has been associated with computer use.

Included in this formula is a lutein to zeaxanthin ratio of 3:1, which has been shown in research to support the macula and healthy vision.† Additionally, nutrients such as vitamin C, alpha-lipoic acid, green tea, and resveratrol provide antioxidant activity to the eyes. Methylated B vitamins in the form of 5-MTHF, methylcobalamin, P-5-P and benfotiamine allow for maximum bioavailability of these nutrients.

Blue Light & Free Radicals

Blue light vision damage is the term used for vision damage caused by blue light emitted from electronic devices. It comes from the use of computers, laptops, tablets, smartphones and LED TVs, as well as the sun, fluorescent lighting and LED lighting. All of these devices emit blue light, which is at the lower end of the light spectrum. People protect their eyes from the harmful UV rays of the sun by wearing protective sunglasses, but now there is a need to protect our eyes the harmful UV rays of the sun by wearing protective sunglasses, but now there is a need to protect our eyes from blue light damage as well.

Recent studies have shown that people who use electronic devices regularly have developed eye-related problems. Blue light is the secret culprit behind people developing vision issues such as dry eyes, blurry vision, and more. Some research has even indicated that people that use electronic devices religiously have developed macular degeneration. Overexposure to blue light has also been associated with unexplained weight gain, sleep deprivation, insomnia, attention deficit disorder and sleep apnea.

In recent times, there has been a significant increase in the use of digital devices and modern lighting such as LED lights and compact fluorescent lamps which emit a high level of blue light. Compact fluorescent lamps emit 25% harmful blue light and LED lights emit 35% harmful blue light. By 2020, 90% of all of our light sources are estimated to be LED lighting. Exposure to blue light is everywhere and projected to increase.

Free radicals are toxic molecules that are highly reactive with other cellular structures because they contain unpaired electrons. Free radicals can cause damage to parts of cells such as proteins, DNA, and cell membranes by stealing their electrons. Free radical-generation can be caused by the food we eat, the drugs and medicines we take, the air we breathe, the water we drink and the computers we use.

All computers and many electronic devices emit radiation or electromagnetic fields (EMFs) on many different frequencies. These EMFs emit dangerous free radicals that can be extremely harmful to your health. Cancer and other serious diseases have been linked to these exposures. EMFs may affect biological systems by increasing free radical life span and the concentration of free radicals in the eye.

Functions

More than any tissues in the body, the ocular lens and retina are continually exposed to free radical damage and intense light radiation. Both light and oxygen can create free radicals that disturb membrane lipids of visual cells. Experts believe that the uncontrolled generation of free radicals in the eyes can ultimately lead to degeneration of the macula with vision loss or cataracts. Therefore, ocular tissues rely on a strong antioxidant defense system to protect them from free radical damage. OcuStat™ supplies powerful antioxidants in addition to essential basic vitamins and minerals for overall healthy ocular aging.

Extracts of bilberry, grape seed, resveratrol, and green tea are rich sources of flavonoids that provide potent antioxidant defense in retinal visual cells and help maintain healthy vascularization in ocular tissue.† Glutathione and selenium are essential components for healthy activity of the antioxidant enzyme glutathione peroxidase which is abundant in healthy eyes. Glutathione peroxidase levels, however, decline with advancing age, and an adequate dietary supply of glutathione, its precursor N-acetyl-L-cysteine, and selenium may help maintain healthy levels of this important enzyme.† Carotenoids in OcuStat™, such as lutein and zeaxanthin, are also important antioxidants in the macula of the eye as evidenced by recent studies performed by the NIH National Eye Institute. Research has shown that these important carotenoids are the predominant pigments found in the macula and occur naturally in serum at a ratio of 3:1 lutein to zeaxanthin.

Vitamin A functions in the retinal cells as a component of rhodopsin, a light-sensitive pigment that supports night vision. Cofactor minerals zinc and magnesium are found in high concentrations in the ocular tissue. Zinc is not only essential for normal visual signal transduction in the retina, but also is a cofactor for many of the enzymes involved in vitamin A dependent photo-transduction in the rod cells. Moreover, zinc is an essential cofactor of superoxide dismutase (SOD), an antioxidant enzyme that removes potentially dangerous superoxide radicals in the visual cells, the lens, and other tissues. Taurine, the most abundant free amino acid in ocular tissue, is thought to help stabilize neural membranes in retinal cells and modulate photoreceptor activity. A recent study showed a significant improvement in visual function after vitamin D supplementation, suggesting that vitamin D-3 supports the retina and age-related vision. †

OcuStat™ contains methylated B vitamins for increased bioavailability to the body, including benfotiamine, a fat-soluble form of thiamine. Metafolin®, a patented, natural form of (6S) 5- methyltetrahydrofolate (5-MTHF) is the naturally occurring, predominant form of folate commonly found in cells and is essential for retinal health and methylation support. Unlike synthetic folic acid, L-methylfolate can be used directly by the body, without the need for an additional conversion via the enzyme (5,10 methylenetetrahydrofolate reductase (MTHFR)). In certain populations, the body’s ability to convert folic acid to 5-MTHF by use of this enzyme may be compromised due to genetic differences. Metafolin® contains only the S isomer of 5-MTHF and has been shown to be the only form of folate to be able to cross the blood-brain barrier.

Indications

OcuStat™ is indicated for individuals that desire the essential vitamins, minerals, and nutrients for maintaining healthy vision and ocular function during computer use.

Formula

Other Ingredients: Hydroxypropyl methylcellulose (capsule), cellulose, vegetable stearate, silica.

Suggested use - As a dietary supplement, adults take 4 capsules daily in divided doses with meals or as directed by your healthcare professional.

Side Effects - No adverse effects have been reported.

Storage - Store in a cool, dry place, away from direct light. Keep out of reach of children.

References

Muth, ER, Laurent, JM, Jasper, P. Altern Med Rev 2000;5:164-73. [Bilberry].

Chew EY, Clemons TE, Agrón E, Sperduto RD, Sangiovanni JP, Kurinij N, Davis MD; AREDS report no.35. Ophthalmology. 2013 Aug;120(8):1604-1 1 .e4. [V-carotene, and zinc].

Hasselwander, W. Hönlein, L. Schweillert, K. Krömer (2000): Functional foods 2000. [5- Methyltetrahydrofolate].

El-Sayed M. Abdel-Aal. Et al. Nutrients 2013, 5(4), 1169-1185. [Lutein and Zeaxanthin].

Grahn BH, Paterson PG, Gottschall-Pass KT, Zhang Z. JAm Coll Nutr. 2001 Apr;20(2 Suppl):106-18. Review. PubMed PMID: 11349933. [Zinc].

Richer SP, et al. the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. Optometry. 2011 Nov;82(1 1 ):667-680.e6. [Zeaxanthin].

Richer S, et al. The Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr;75(4):21 6-30.

Cavet ME, et al. Mol Vis. 2011 Feb 18;17:533-42. [Green tea].

King RE, Kent KD, BomserJA. Chem Biol Interact. 2005 Jan 15;151(2):143-9. [Resveratrol]. Andrade AS, et al. Exp Eye Res. 2014 Mar;120:1-9. [Alpha lipoic acid].

Shi J, et al. J Med Food. 2003 Winter;6(4):291-9. [Grape Seed Extract].

Hua J, et al. Invest Ophthalmol Vis Sci. 2011 Apr 25;52(5):2809-16. [Resveratrol].

Jerome-Morais A, et al. Biochim Biophys Acta. 2013 Jun;1830(6):3399-406. [Selenium].

Shen H, et al. Environ Sci Pollut Res Int. 2014 May;21(10):6384-99. [Selenium and N-acetylcysteine]. Hartong DT, Berson EL, Dryja TP. Lancet. 2006 Nov 18;368(9549):1795-809.

Dayang W, Jinsong Z. Cutan Ocul Toxicol. 2014 Sep 8:1-6. [Taurine].

Lee V. Neurobiol Aging 2011; 33: 10. [Vitamin D]

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Note: All information on this website is intended for your general knowledge only and is not a substitute for medical advice or treatment for a specific medical condition. Please consult your physician if you have questions or concerns regarding your health.